The critical role and immunological mechanism of activation of FPR and the significance of NADPH oxidase 2 (NOX2)-derived ROS in facilitating neutrophil-mediated eradication of uropathogenic Escherichia coli (UPEC), the primary causative agent of UTI is described in publication from Inicure research partner at Nationwide Children’s hospital (https://www.ncbi.nlm.nih.gov/pubmed/39710133).
