Inicure lead compound characterised as a specific agonist for FPR1, which displays a biased signalling profile that leads to a functional selective activating of the human neutrophils class (https://doi.org/10.1002/JLB.2HI0520-317R).
Functional selective FPR1 signaling in favor of an activationof the neutrophil superoxide generating NOX2 complex
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GoWest 29-30 January
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New publication by Nationwide Childrens hospital in collaboration with Inicure
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Neutrophil NADPH oxidase promotes bacterial eradication and regulates NF-κB-Mediated inflammation via NRF2 signaling during urinary tract infections
The critical role and immunological mechanism of activation of FPR and the significance of NADPH oxidase 2 (NOX2)-derived